Curcumin

Curcumin

Basic Information

CAS No.: 458-37-7
Molecular Formula: C21H20O6
Molecular Weight: 368.38

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product description
Curcumin is usually an orange-yellow crystalline powder. At room temperature, it appears bright yellow with a slight earthy smell and is odorless. At normal pressure, the boiling point is approximately 418.73°C (rough estimate). Some data also show that at a pressure of 760mmHg, the boiling point is 591.4°C. Slightly soluble in water and slightly soluble in hot water; It is readily soluble in glacial acetic acid and soluble in organic solvents such as ethanol, acetone, ether and dichloromethane.


Chemical Properties
PropertyValue

Melting point

183 °C

Boiling point

418.73°C (rough estimate)

Density

0.93

Vapor density

13 (vs air)

Refractive index

1.4155-1.4175

Fp

208.9±23.6 °C

Storage temp.

2-8°C

Solubility

ethanol: 10 mg/mL

Form

powder

Colour Index

75300

Pka

8.09(at 25℃)

Color

orange

PH Range

Yellow (7.8) to red-brown (9.2)

Odor

Odorless

Biological source

Curcuma longa (Turmeric)

Water Solubility

Slightly soluble (hot)

λmax

430nm

Merck

14,2673

Solvent

Ethanol

Concentration

1 mCi/ml

Specific Activity

5-15 Ci/mmol

BRN

2306965

Stability

Stable, but may be light sensitive. Incompatible with strong oxidizing agents.

Major Application

Cosmetics, drug-eluting stents, inhibition of formation of skin-wrinkles, treating alzheimer’s disease, skin diseases, coronary restenosis, diabetes, obesity, leukemia, neurofibromas, cancer, antimicrobial, antiviral, antiinflammatory, antiprostate cancer

InChIKey

VFLDPWHFBUODDF-FCXRPNKRSA-N

LogP

3.290 (est)

CAS DataBase Reference

458-37-7(CAS DataBase Reference)

EPA Substance Registry System

Curcumin (458-37-7)


Safety Information

PropertyValue
Hazard symbolXi
Hazard class codes36/37/38
Safety descriptions26
WGK Germany3
RTECS numberMI5230000
Hazard NoteIrritant
TSCATSCA listed
HS code29145000
Storage class11 - Combustible solids
Hazardous substances data458-37-7 (Hazardous Substances Data)
ToxicityLD50 Oral-Rat-12.200 mg/kg


Product Usage

Curcumin is a natural bioactive compound derived from turmeric, widely used in research for its antioxidant, anti-inflammatory, and anticancer properties. It is commonly studied in cell signaling pathways (e.g., NF-κB, MAPK), neuroprotection, and metabolic disorders. For laboratory and research use only.

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