Arbutin

Arbutin

Basic Information

CAS No.: 497-76-7
Molecular Formula: C12H16O7
Molecular Weight: 272.25

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product description
Arbutin is a β-D-glucopyranoside HQ derivative and a plant-derived compound found in the dried leaves of several plant species, including blueberry, cranberry, bearberry, and pear trees. It suppresses tyrosinase activity without altering RNA expression.


Chemical Properties
PropertyValue

Melting point

195-198 °C

Alpha

-64 º (c=3)

Boiling point

375.31°C (rough estimate)

Density

1.3582 (rough estimate)

Refractive index

-65.5 ° (C=4, H2O)

Storage temp.

Inert atmosphere,Room Temperature

Solubility

H2O: 50 mg/mL hot, clear

Pka

10.10±0.15(Predicted)

Form

Solid

Color

White

Biological source

Synthetic or plant

Optical Rotation

[α]/D -64.0±2.0°, c = 3 in H2O

Water Solubility

10-15 g/100 mL at 20 ºC

Sensitive

Hygroscopic

Merck

14,773

BRN

89673

Stability

Stable. Hygroscopic - store under dry nitrogen.

InChIKey

BJRNKVDFDLYUGJ-RMPHRYRLSA-N

LogP

-1.350

CAS DataBase Reference

497-76-7(CAS DataBase Reference)

EPA Substance Registry System

.beta.-D-Glucopyranoside, 4-hydroxyphenyl (497-76-7)


Safety Information

PropertyValue

Hazard Codes

Xn

Risk Statements

20/21/22-36/37/38

Safety Statements

22-24/25-36-26

WGK Germany

3

RTECS

CE8863000

F

3-10-23

HS Code

29389090

Hazardous Substances Data

497-76-7(Hazardous Substances Data)


Product Usage

Arbutin, a naturally derived hydroquinone glucoside typically extracted from bearberry leaves, is a premier active ingredient in the global cosmetic and skincare industry. It is primarily utilized as a safe and effective skin-lightening agent in brightening serums, whitening creams, and spot-correction treatments. By competitively inhibiting tyrosinase activity, it effectively suppresses melanin production to fade hyperpigmentation, melasma, and post-inflammatory dark spots. In the personal care sector, Arbutin is highly valued for its dual functionality, offering both depigmenting effects and potent antioxidant properties that protect the skin against oxidative stress induced by UV radiation. Furthermore, its mild nature compared to synthetic alternatives makes it an ideal component for sensitive skin formulations and high-end dermo-cosmetics aimed at evening out skin tone and restoring a youthful, radiant complexion.

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FAQ

Q1: What international standards do your products and services comply with?

A1: Our products fully comply with international standards such as REACH, MSDS, and COA, and we strictly implement the ISO9001 quality management system. We can also provide third-party testing reports (SGS, BV, etc.) according to customer needs.


Q2: How long does it take for goods to be delivered to my country?
A2: The delivery time depends on the transport mode and destination country. Generally, sea transport takes 15-30 days, air transport takes 3-7 days, and we will optimize the transport route to shorten the delivery time as much as possible.


Can you provide customs clearance services for dangerous chemicals?
A3: Yes. Our team is proficient in the customs clearance procedures for dangerous chemicals in various countries, and can provide professional compliant declaration and customs clearance services to ensure smooth customs clearance.


Q4: Do you provide customized product and service solutions?
A4: Yes. We can provide personalized product customization and export service solutions according to your specific needs (product specifications, application scenarios, procurement volume, etc.).

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