Cholesterol

Cholesterol

Basic Information

CAS No.: 57-88-5
Molecular Formula: C27H46O
Molecular Weight: 386.65

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product description
Cholesterol is a waxy, fatty substance that exists in all cells of the body. It is produced in the liver, but can also be found in some foods. Cholesterol is essential for the normal functioning of the body as it helps in the production of hormones, vitamin D and bile acids. Cholesterol is carried in the blood through proteins, and proteins and cholesterol combine through proteins, which are called lipoproteins.


Chemical Properties
PropertyValue

Melting point

148-150 °C

Alpha

-36 º (c=2, dioxane)

Boiling point

360 °C

Density

1.06

Refractive index

1.5250 (estimate)

Fp

250 °C

Storage temp.

-20°C

Solubility

H2O: 0.002 mg/mL

Form

Powder

pka

15.03±0.70(Predicted)

color

White

Specific Gravity

1.067

Odor

wh. or faintly yel. pearly granules or crystals, almost odorless

Biological source

Synthetic

Optical Rotation

-40.201°(C=0.01g/ml CHCL3)

Water Solubility

Negligible

Merck

14,2201

BRN

1915888

Dielectric constant

2.9(Ambient)

InChIKey

HVYWMOMLDIMFJA-DPAQBDIFSA-N

LogP

9.619 (est)

CAS DataBase Reference

57-88-5(CAS DataBase Reference)

NIST Chemistry Reference

Cholesterol(57-88-5)

IARC

3 (Vol. 31, Sup 7) 1987

EPA Substance Registry System

Cholesterol (57-88-5)


Safety Information
PropertyValue

Hazard Codes

Xn,Xi

Risk Statements

10-48/20/22-40-38-22-36/37/38-67-36/38-20-63

Safety Statements

24/25-22-36/37-36-26

RIDADR

UN 1170 3/PG 3

WGK Germany

1

RTECS

FZ8400000

TSCA

Yes

HS Code

2906 13 10

HazardClass

IRRITANT

Hazardous Substances Data

57-88-5(Hazardous Substances Data)

Toxicity

Present in all parts of the animal body; concentrated in spinal cord, brain, skin secretions, and gallstones. An unsaturated, unsaponifiable alcohol (m.p. 149℃). It is synthesized in the body from ethanoate units; its metabolism is regulated by a specific set of enzymes. It is the parent compound of many other steroids and its presence in high concentrations in the blood is suspected as being a contributory factor in cardiovascular disease.


Product Usage

Cholesterol is a vital lipid and a fundamental structural component of cell membranes, widely utilized in the pharmaceutical and cosmetic industries. Its primary application is in the production of liposomes, which serve as advanced drug delivery systems to enhance the stability and absorption of active ingredients. In the pharmaceutical sector, it is a critical precursor for synthesizing Vitamin D3 and various steroid hormones. In cosmetics and skincare, cholesterol is a key ingredient in "skin-identical" formulations, helping to restore the skin barrier, improve moisture retention, and provide anti-aging benefits. Additionally, high-purity cholesterol is used in biotechnology as a cell culture supplement to support the growth of specialized cell lines and in the shrimp feed industry as an essential nutrient for crustacean growth and molting.

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